Corneal Densitometry Changes With Adenoviral SEI

Benha University

Status: Completed

Conditions: Corneal Disease

Treatments: Drug: Tacrolimus ointment; Procedure: phototherapeutic keratectomy

Study type: Observational

Funder types: Other

Identifiers

NCT04267991

Hamaky5

Details and patient eligibility

About

Adenoviral Sub epithelial infiltrates (SEI) affect ocular function.They lead to reduced vision, photophobia, glare, halos, and foreign body sensation.

Full description

first group of patients were treated with 0.03 % tacrolimus ointment twice daily for 6 months.S econd group underwent transepithelial PTK for subepithelial infiltrates. Baseline and post-treatment full ophthalmic examination was done.

Enrollment: 63 patients

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• adenoviral SEI

Exclusion criteria

• Other corneal diseases

Trial design

63 participants in 3 patient groups

Tacrolimus

Description:

Patients were treated with 0.03 % tacrolimus ointment twice daily for 6 months.

Treatment:

Drug: Tacrolimus ointment

Phototherapeutic Keratectomy

Description:

Patients underwent transepithelial PTK for subepithelial infiltrates.

Treatment:

Procedure: phototherapeutic keratectomy

Control

Description:

patients received only artificial tears eyedrop