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Corneal Endothelial Cell Loss in Diabetes Type II During Cataract Surgery

F

Frederiksberg University Hospital

Status

Suspended

Conditions

Diabetes Mellitus

Treatments

Procedure: cataract surgery

Study type

Observational

Funder types

Other

Identifiers

Details and patient eligibility

About

The aim of the present study is to evaluate changes in the morphology and function of the corneal endothelium before and after cataract surgery in patients with diabetes type II. Also to explain if determination of HgbA1c in diabetics is a predictor for the changes in morphology and function.

Full description

Thirty patients with Diabetes type II and thirty non-diabetes patients scheduled to cataract surgery (phacoemulsification with intraocular lens implantation) were invited to participate in the study. Preoperatively, all patients had a full eye examination and 3 endothelial cell photos were taken.

Three months postoperatively the patients were called for a re-examination including 3 endothelial cell photos. The function of the cornea is dependent of the number and morphology of the endothelial cells, and even small traumas like cataract surgery may disrupt the cornea integrity leading to corneal haze and blur. Diabetics may be more vulnerable to corneal stress.

Enrollment

30 estimated patients

Sex

All

Ages

50+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Patients with cataract scheduled for surgery

Exclusion criteria

  • Patients with corneal diseases, glaucoma or uveitis, previous intraocular surgery or eye traumas.

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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