Corneal Endothelial Changes Following Pediatric Cataract Surgery With IOL Implantation

Iladevi Cataract and IOL Research Center

Status: Completed

Conditions: Congenital Cataract Surgery; Change in Corneal Endothelial Cell Morphology; IOL Implantation

Treatments: Procedure: Congenital Cataract Surgery

Study type: Observational

Funder types: Other

Identifiers

NCT01504607

ICIRC-Pedspec

2011-13

Details and patient eligibility

About

Cataract surgery is known to cause loss of corneal endothelial cells. In adults, it is reported that anywhere between 2 to 15% loss of corneal endothelial cell density occurs following cataract surgery. However, no data is available regarding endothelial changes after cataract surgery with IOL implantation in pediatric eyes.

The aim of this study is to prospectively observe changes in endothelial cell density, coefficient of variation and hexagonality following cataract surgery with IOL implantation in pediatric eyes.

Enrollment: 106 patients

Sex: All

Ages: 4 to 15 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Eyes undergoing pediatric cataract surgery with IOL implantation at Iladevi Cataract & IOL Research Center, Ahmedabad, India.
• Children older than 4 years undergoing cataract surgery with IOL implantation were included.

Exclusion criteria

• Exclusion criteria were as follows: eyes with traumatic or subluxated cataract and inability to get preoperative specular. Intraoperatively, sulcus fixated IOLs, and eyes with no IOL implantation were excluded.

Trial design

106 participants in 1 patient group

Congenital cataract surgery with IOL implantation

Description:

Congenital cataract surgery was performed with or without anterior vitrectomy, followed by in the bag IOL implantation

Treatment:

Procedure: Congenital Cataract Surgery