Coronally Advanced Flap in Combination With Acellular Dermal Matrix and Enamel Matrix Derivatives for Root Coverage

Tabriz University

Status and phase: Completed; Phase 4

Conditions: Gingival Recession

Treatments: Procedure: CAF+ADM; Procedure: CAF+ADM+EMD

Study type: Interventional

Funder types: Other

Identifiers

NCT00720707

841

Details and patient eligibility

About

The aim of this study is to compare the clinical outcomes of root coverage procedures, using coronally advanced flap in combination with acellular dermal matrix with or without enamel matrix derivatives .

Full description

coverage of gingival recession defects has been considered as a matter of interest for dental practitioners.subjects with a paired gingival recession defect will be selected from the patients who sought dental treatment at our department.Random allocation of the treatment sites to test (CAF+ EMD+ADM) and control (CAF + ADM) groups will be performed by a person who is external to the study and using a computerized selection of random numbers for allocation of the study groups.The parameters of the study are as following items: probing depth( PD), clinical attachment level (CAL), width of keratinized tissue (WKT), recession depth from cemento- enamel junction (RD), recession width (RW), distance between mucogingival junction and the stent (MGJ), Plaque (PI) and gingival (GI) indices and root coverage percentage (RC) and the patients will be followed up for 6 months.

Enrollment: 18 patients

Sex: All

Ages: 20 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Having no systemic disease affecting the periodontium,
• No contraindication for elective surgery,
• Adequate oral hygiene ,
• No previous surgical attempts for root coverage at the studying sites,
• Vital teeth and signing a witness letter.

Exclusion criteria

• Smoking, presence of a restorations on tooth surface for test and control teeth,
• Pregnancy,
• Being under treatment with steroids,
• Peri-apical infection,
• Indication for antibiotic prophylaxis prior to dental treatments

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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18 participants in 2 patient groups

(CAF+ADM+EMD)

Experimental group

Description:

using coronally advanced flap (CAF) in combination with acellular dermal matrix (ADM) with enamel matrix derivatives (EMD).

Treatment:

Procedure: CAF+ADM+EMD

(CAF + ADM)

Active Comparator group

Description:

root coverage procedure by using a coronally advanced flap (CAF) in combination with acellular dermal matrix (ADM)

Treatment:

Procedure: CAF+ADM