Coronary Atherosclerosis Evaluation by Arterial Wall Magnetic Resonance Imaging (MRI)

Johns Hopkins University

Status

Completed

Conditions

Coronary Artery Disease

Coronary Atherosclerosis

Atherosclerosis, Coronary

Coronary Arteriosclerosis

Arteriosclerosis, Coronary

Treatments

Procedure: MR Imaging of the Coronary Arteries

Study type

Interventional

Funder types

Other

Identifiers

NCT00353795

5R01HL078909 (U.S. NIH Grant/Contract)

05-05-23-01

Details and patient eligibility

About

The overall goal of this study is to use MRI to:

Examine the relationship between known risk factors for cardiovascular disease and coronary artery wall thickness;
Examine the relationship between coronary artery wall thickness and other markers of subclinical coronary atherosclerosis, such as carotid wall thickness and coronary calcium scores; and,
Examine the feasibility of measuring the progression of coronary artery wall thickness over time in a subset of participants.

Full description

Each enrolled participant will undergo MR Imaging of the coronary arteries in conjunction with their routine MESA follow-up visit. The MRI will last approximately 45-60 minutes

Enrollment

179 patients

Sex

All

Ages

45+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Prior enrollment in the MESA Study at the Hopkins MESA Field Center or the Northwestern University MESA Field Center
Male or Female adult equal to or older than 45 years of age
Willing/able to provide informed consent

Exclusion criteria