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Coronary Interventions Ulm - Coronary Chronic Total Occlusions (CSI)

U

University Hospital Ulm

Status

Enrolling

Conditions

Chronic Total Occlusion
Chronic Total Occlusion of Coronary Artery

Treatments

Procedure: PCI - percutaneous coronary intervention

Study type

Observational

Funder types

Other

Identifiers

NCT04650139
0925-0586

Details and patient eligibility

About

The aim of the proposed project is to provide the long-term results after a recanalization attempt of chronically occluded coronary arteries.

To investigate recanalization attempt of chronically occluded coronary arteries at the Ulm University Hospital. As shown, it is known that successful recanalization of a chronic occlusion is associated with a lower event rate (reduced mortality and the need for operative myocardial revascularization) compared to unsuccessful recanalization (drug therapy). The standard in the therapy of successfully recanalized chronic occlusions is the use of drug-releasing vascular supports.

Enrollment

500 estimated patients

Sex

All

Ages

18+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Patients over 18 years

Coronary intervention in chronic coronary artery occlusion

Occlusion > 3 months

Indication for PTCA or recanalization according to guidlines

such as:

Symptoms of the patient

Evidence of myocardial ischemia (stress ECG, scintigraphic

Methods, magnetic resonance imaging, stress echocardiography)

pathological intracoronary flow reserve, prognostic

Exclusion criteria

  • No chronic occlusion,
  • Contraindication to anti-platelet therapy

Acetylsalicylic acid plus clopidogrel for at least 3 months such as e.g.

with florid gastrointestinal ulcer disease,

History of hemorrhagic stroke

or urgent non-postponable surgical intervention.

Basic disease with a life expectancy of less than 12 months (here as a rule

no indication for PTCA or reopening available)

Trial design

500 participants in 2 patient groups

successful CTO
Treatment:
Procedure: PCI - percutaneous coronary intervention
non- successful CTO
Treatment:
Procedure: PCI - percutaneous coronary intervention

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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