Coronary Microvascular Dysfunction in Angina Patients With Non-obstructive Coronary Artery Disease (ANOCA-CMD)

China-Japan Friendship Hospital

Status: Enrolling

Conditions: Angina Patients With Non-obstructive Coronary Artery Disease; Index of Microvascular Resistance; Coronary Microvascular Dysfunction

Study type: Observational

Funder types: Other

Identifiers

NCT06503640

2023-KY-077

Details and patient eligibility

About

The goal of this observational study is to explore the incidence and effect on prognosis of coronary microvascular dysfunction in patients present of stable anginal symptoms, a clinical indication for invasive coronary angiography, and no hemodynamically significant epicardial coronary artery disease, defined as fractional flow reserve (FFR) >0.80.

Enrollment: 100 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• presence of stable anginal symptoms, a clinical indication for invasive coronary angiography, and no hemodynamically significant epicardial coronary artery disease, defined as fractional flow reserve (FFR) >0.80

Exclusion criteria

1. acute myocardial infarction
2. significant valvular heart disease
3. advanced chronic kidney disease
4. patients with significant epicardial coronary artery stenosis (>70% in major vessels by diagnostic coronary angiography) needing percutaneous coronary intervention
5. patients unable to provide written informed consent