Coronary Revascularization in Patients With Dialysis in China (CRUISE)

China-Japan Friendship Hospital

Status: Unknown

Conditions: Coronary Artery Disease; Dialysis; Intervention

Treatments: Other: Medical therapy; Other: Revascularization

Study type: Observational

Funder types: Other

Identifiers

NCT04953819

2020-112-K71

Details and patient eligibility

About

China patients in end stage renal disease receiving maintenance dialysis have a high risk of cardiovascular disease (CVD), with a prevalence of 45.5% approximately, and coronary artery disease (CAD) has been identified as the most common one. It remains unclear that what their treatment status is and whether this group of patients can benefit from revascularization in China. The investigators plan to recruit around 30 hospitals from 7 regions as study centers, which represent different levels of economic development in Mainland China. The detailed information includes demographics, medical history, coronary angiogram, in-hospital treatment and procedures, short-term and long-term outcomes. The aim of the study is to provide the real world knowledge about current status of coronary revascularization and prognosis in patients with CAD and dialysis.

Enrollment: 1,000 estimated patients

Sex: All

Ages: 18 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Aged 18 or above and 85 or below.
• Receives peritoneal dialysis or hemodialysis more than 1-time weekly and for more than 3 months.
• Diagnosed with coronary artery disease, including STEMI, NST-ACD, stable coronary artery disease.

Exclusion criteria

• Pregnancy or lactation.
• Can't be cooperative because of a mental illness or other reasons.
• Malignant tumor or severe hepatic disease.
• Life expectancy is less than 1 year.

Trial design

1,000 participants in 2 patient groups

Revascularization group

Description:

This group includes patients with dialysis who have received revascularization by percutaneous coronary intervention or coronary artery bypass grafting for coronary artery disease.

Treatment:

Other: Revascularization

Medical treatment group

Description:

This group includes patients who have received medical therapy for coronary artery disease, not percutaneous coronary intervention or coronary artery bypass grafting.

Treatment:

Other: Medical therapy