CORonavirus (COVID-19) Diagnostic Lung UltraSound Study (COR-DLUS)

University Hospital Plymouth NHS Trust

Status: Completed

Conditions: COVID-19

Treatments: Diagnostic Test: Lung ultrasound

Study type: Observational

Funder types: Other

Identifiers

NCT04351802

282661

Details and patient eligibility

About

This observational study is designed to assess whether focused lung ultrasound examination can improve the diagnosis of COVID-19 lung disease and/or make an alternative diagnosis at a patient's initial hospital presentation. For patients with confirmed COVID-19 the study will also assess whether surveillance lung ultrasound examination can predict clinical outcome over the course of their hospital admission.

Full description

Study participants will be screened from and recruited on their entry into the suspected COVID-19 admission pathway at Derriford Hospital, Plymouth, UK. In addition to usual clinical care (including physical exam and observations, blood tests, nasopharyngeal swab for viral PCR testing, and chest x-ray as standard), participants will undergo focused lung ultrasound examination.

Participants who are negative for COVID-19 will be followed up to confirm their final discharge diagnoses, and clinical outcome at either 3 months post-enrolment or discharge from hospital.

Participants who are positive for COVID-19 will have regular focused lung ultrasound examination during their hospital admission in addition to usual clinical care until their treatment for COVID-19 is complete. Their discharge diagnoses and clinical outcome at either 3 months post-enrolment or discharge from hospital (whichever is later).

Enrollment: 45 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age greater than or equal to 18 years
• Suspected or confirmed diagnosis of COVID-19
• Able to provide informed consent to study participation

Exclusion criteria

• Age less than 18 years
• Inability to provide informed consent at the time of study enrolment