COronaVirus Induced Acute Respiratory Disease Syndrome During PREGnancy (COVADIS-PREG)

Centre Hospitalier Intercommunal Creteil

Status: Active, not recruiting

Conditions: Acute Respiratory Distress Syndrome Related to SARS-CoV-2

Treatments: Other: No intervention

Study type: Observational

Funder types: Other

Identifiers

NCT05193526

COVADIS PREG

Details and patient eligibility

About

Few data are available on the management of critically ill pregnant women with pneumonia related to SARS-CoV-2. In the absence of clear recommendations for the management of delivery, clinicians are faced with the risk of pregnancy continuation against the risk of premature birth. In these multicenter retrospective study, the investigators want to describe clinicians attitude on delivery management in pregnant women requiring invasive mechanical ventilation for acute respiratory distress syndrome related to SARS-CoV-2.

Two strategies will be compared on maternal, obstetric and neonatal outcomes:

• Wait strategy defined by no extraction within 24 hours of invasive venting
• Early strategy defined by extraction within 24 hours of invasive ventin

Enrollment: 100 estimated patients

Sex: Female

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

1. patient > 18 years
2. Patient with SARS-CoV-2 pneumonia proven by RT-PCR
3. Hospitalization in an intensive care unit during pregnancy after 14 weeks' gestation
4. Need for ventilatory support including: oxygen therapy > 6L/min and/or NIV and/or High Flow Oxygen and/or invasive mechanical ventilation +/- ECMO.

Exclusion Criteria:

• Patient's refusal to participate in this study