Coronavirus Infection (COVID-19) and Radical Surgery in Patients With Early-stage Lung Cancer (COVIDLungSurg)

Shanghai Jiao Tong University

Status: Active, not recruiting

Conditions: Corona Virus Infection; Surgery

Treatments: Other: No intervention

Study type: Observational

Funder types: Other

Identifiers

NCT05684549

RTS-017

Details and patient eligibility

About

The goal of this observational study is to learn about the effects of coronavirus infection in patients with early-stage lung cancer. The main question it aims to answer is whether the interval of surgery and COVID-19 infection will affect the surgery and prognosis of the patients.

Enrollment: 2,000 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Clinically diagnosed stage I and stage II lung cancer, who are about to receive wedge resection, segmental resection, sleeve resection, lobectomy, or pneumonectomy under general anaesthesia.
• Volunteer to participate in the study with good compliance. Able to complete the observation and follow-up and have signed the informed consent.
• ASA score: I-III;
• Cardiopulmonary functions meet the requirements of radical operation for lung cancer with normal liver and kidney functions.

Exclusion criteria

• Neurologic, mental illness or mental disorder which is hard to control, poor compliance, unable to cooperate or describe the treatment response;
• Clinically diagnosed stage III and stage IV lung cancer or patients who received neoadjuvant treatment before surgery;
• Patients developed symptoms alike coronavirus infection but are not confirmed by viral RNA detection by quantitative RT-PCR or antigen testing kits.
• Serious heart, lung, liver and kidney dysfunction and unable to tolerate the operation

Trial design

2,000 participants in 1 patient group

stage I/II lung cancer patients

Description:

Patients with stage I/II lung cancer will receive radical surgery.

Treatment:

Other: No intervention