Correlates of Left Ventricular Global Longitudinal Strain and Surgical Intervention on Myocardial Bridges

ITAB - Institute for Advanced Biomedical Technologies

Status: Completed

Conditions: Myocardial Bridge of Coronary Artery

Treatments: Procedure: Surgical unroofing of muscle-briged coronary artery

Study type: Observational

Funder types: Other

Identifiers

NCT04082546

CCPC001

Details and patient eligibility

About

To examine the changes in left ventricular (LV) global longitudinal strain (GLS), using two-dimensional speckle tracking analysis, after left anterior descending (LAD) unroofing, in myocardial bridges (MBs) refractory to optimal medical therapy (OMT).

Full description

The present study is enrolling all the MBs-patients who underwent angina surgical relief or medical treatment at the "Ospedali Riuniti" of Ancona, Italy, and the "University Hospital" of Chieti, Italy. All the participants will be examined utilizing echocardiography before and after the treatment. The two-dimensional speckle-tracking analysis will be performed with an off-line dedicated software from the apical 4-chambers-view. All the unroofing procedures will be performed under cardiopulmonary bypass.

Enrollment: 10 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Myocardial bridge of the anterior descending left coronary artery

Exclusion criteria

• Poor echocardiographic imaging quality

Trial design

10 participants in 2 patient groups

Surgical unroofing

Description:

Refractory angina to medical treatment (beta-blockers or calcium channels blockers)

Treatment:

Procedure: Surgical unroofing of muscle-briged coronary artery

Medical treatment

Description:

Responders to medical treatment for angina relief

Treatment:

Procedure: Surgical unroofing of muscle-briged coronary artery