Correlation Between Altered Glycometabolic Status and Joint Inflammation in Diabetic Patients With Osteoarthritis Undergoing Knee Arthroplasty (GLICO PG)

I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio

Status: Enrolling

Conditions: To Evaluate a Linear Positive Correlation Between Plasma HbA1c and Synovial IL-6 in Diabetic Patients

Treatments: Diagnostic Test: Evaluation of Synovial IL-6 in diabetic patients with gonarthrosis

Study type: Observational

Funder types: Other

Identifiers

NCT05150119

GLICO PG

Details and patient eligibility

About

Evaluate the correlation between altered glycometabolic status and joint inflammation in diabetic patients with osteoarthritis undergoing knee replacement surgery

Enrollment: 40 estimated patients

Sex: All

Ages: 55 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diabetic patients
• Patients with osteoarthritis awaiting knee replacement surgery
• Patients awaiting knee replacement surgery
• Patients who agree to sign informed consent

Exclusion criteria

• Patients less than 55 years of age.
• Patients over 85 years of age.
• Patients who are unable to understand and want.
• Patients with severe neurological disorders or with severe disabilities.
• Rheumatoid arthritis patients
• Cancer patients
• Patients suffering from chronic inflammatory bowel syndromes (RCU and Crohn's disease)
• Patients on immunosuppressive therapy