Correlation Between Angle Closure Glaucoma Data and Lens Zonule Status

Guangfu Dang

Status: Completed

Conditions: Primary Angle Closure Glaucoma

Study type: Observational

Funder types: Other

Identifiers

NCT06184620

YXLL-KY-2023(047)

Details and patient eligibility

About

The goal of this observational study is to discuss the correlation between primary angle-closure glaucoma and the state of the suspended ligament of the lens and the pathogenesis of PACG by measuring the biological data of primary angle-closure glaucoma and observing its anatomical changes.

Full description

Patients clinically diagnosed with Primary angle-closure glaucoma (PACG) and normal control patients from December 2020 to January 2022 were enrolled in this study.

Enrollment: 263 patients

Sex: All

Ages: 47 to 91 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• The depth of the anterior chamber is normal, and the whole corner of the chamber is open;
• The cup-to-plate ratio is less than 0.5;
• No family history of glaucoma.

Exclusion criteria

• Previous history of trauma or internal eye surgery in both eyes or one eye;
• Used "pilocarpine", "atropine" and other drugs to change the size of the pupil and the shape of the chamber Angle within 1 week;
• Combined with other eye diseases affecting the Angle and suspension ligament, such as uveitis, ciliary cyst, high myopia, retinal diseases, etc.;
• Can not cooperate with UBM and Angle scopy;
• Refuse to participate in this researcher.

Trial design

263 participants in 2 patient groups

PACG group

Description:

All patients in the experimental group met the diagnostic criteria of primary angle-closure glaucoma in the Chinese Glaucoma Guidelines(2020).

control group

Description:

The depth of the anterior chamber is normal, and the whole corner of the chamber is open; The cup-to-plate ratio is less than 0.5; No family history of glaucoma