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Correlation Between Angle Closure Glaucoma Data and Lens Zonule Status

G

Guangfu Dang

Status

Completed

Conditions

Primary Angle Closure Glaucoma

Study type

Observational

Funder types

Other

Identifiers

NCT06184620
YXLL-KY-2023(047)

Details and patient eligibility

About

The goal of this observational study is to discuss the correlation between primary angle-closure glaucoma and the state of the suspended ligament of the lens and the pathogenesis of PACG by measuring the biological data of primary angle-closure glaucoma and observing its anatomical changes.

Full description

Patients clinically diagnosed with Primary angle-closure glaucoma (PACG) and normal control patients from December 2020 to January 2022 were enrolled in this study.

Enrollment

263 patients

Sex

All

Ages

47 to 91 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • The depth of the anterior chamber is normal, and the whole corner of the chamber is open;
  • The cup-to-plate ratio is less than 0.5;
  • No family history of glaucoma.

Exclusion criteria

  • Previous history of trauma or internal eye surgery in both eyes or one eye;
  • Used "pilocarpine", "atropine" and other drugs to change the size of the pupil and the shape of the chamber Angle within 1 week;
  • Combined with other eye diseases affecting the Angle and suspension ligament, such as uveitis, ciliary cyst, high myopia, retinal diseases, etc.;
  • Can not cooperate with UBM and Angle scopy;
  • Refuse to participate in this researcher.

Trial design

263 participants in 2 patient groups

PACG group
Description:
All patients in the experimental group met the diagnostic criteria of primary angle-closure glaucoma in the Chinese Glaucoma Guidelines(2020).
control group
Description:
The depth of the anterior chamber is normal, and the whole corner of the chamber is open; The cup-to-plate ratio is less than 0.5; No family history of glaucoma

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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