Correlation Between ΔPP/HR and ΔSV During Fluid Challenge. (ΔPP/HRvsΔSV)

Caen University Hospital

Status: Unknown

Conditions: Hypovolemia

Treatments: Drug: fluid challenge of saline

Study type: Observational

Funder types: Other

Identifiers

NCT02439242

ΔPP/HR vs ΔSV

Details and patient eligibility

About

In high perioperative risk patients, guidelines suggest intraoperative haemodynamic optimization by measurement of stroke volume (SV) to guide fluid resucitation.This strategy requires an invasive monitoring and learning. Some studies tried to find SV surrogates based on haemodynamic usual parameters. In an experimental hemorrhagic shock, SV was correlated to the pulse pressure (PP) / heart rate (HR) ratio.

The investigators hypothesized that SV variations (ΔSV) would be correlated to the PP/HR ratio variations (ΔPP / HR) during fluid challenge, and ΔPP / HR would be able to detect a ΔSV greater than 10%.

Enrollment: 100 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• a suspected hypovolemia, based on clinical or paraclinical parameters.
• a fluid challenge decision at the discretion of the anaesthesiologist physician in charge of the patient.

Exclusion criteria

• Minor or major patient under guardianship,
• oesophageal Diseases