Correlation Between External Jugular Venous and Superior Vena Cava Central Venous Blood Oxygen Saturation in Patient Under General Anesthesia

Mahidol University

Status: Unknown

Conditions: Central Venous Oxygen Saturation

Study type: Observational

Funder types: Other

Identifiers

NCT04017182

04072019

Details and patient eligibility

About

After installation of central venous catheter in patients under general anesthesia, paired sample of superior vena cava central venous blood and right external jugular venous blood will be collected and send to central laboratory for venous blood gas analysis. Correlation between superior vena cava central venous blood and right external jugular venous blood oxygen saturation will be determined as primary outcome.

Full description

All patients age between 18-65 year old who undergoing surgery under general anesthesia and superior vena cava central venous catheter installation anticipated are eligible. The tips of superior vena cava central venous catheter was confirmed by Chest x-ray. Next 1 hour after skin incision, 1 ml of venous blood sample is taken from superior vena cava central venous catheter of right external jugular vein then send to central laboratory for venous blood gas analysis. The demographic data will be recorded. Correlation between superior vena cava central venous blood and right external jugular venous blood oxygen saturation will be determined the primary outcome and partial pressure of carbon dioxide will be determined as a secondary outcome.

Enrollment: 40 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Written consent obtained from patient or next of kin a day before operation date
• Patient age between 18-65 years old undergoing syrgery under general anesthesia
• Superior vena cava central venous catheter anticipated for CVP mesurement, innotropic or vasopressor administration,pulmonary artery catheter insertion route
• Anticipated right external jugular venous sampling time less than 5 minutes
• The site of blood sample collection easily access during operation

Exclusion criteria

• No jugular central venous catheter installation or other route selected
• Duration of paired sample collection more than 10 minutes
• Can not collected blood sample from right external jugular vein within 3 attemps
• The site of blood sample collection difficulty access during operation
• Pateint or next of kin refuse to participate