Correlation Between Markers of Neuronal Injury and Cognitive Dysfunction After Coronary Artery Bypass Surgery

Maria José Carvalho Carmona

Status: Unknown

Conditions: Postoperative Cognitive Dysfunction

Study type: Observational

Funder types: Other

Identifiers

NCT01550159

1081/04

Details and patient eligibility

About

This study aims to evaluate the possible Correlation Between Serum Levels of Markers of Neuronal Injury and Cognitive Dysfunction after Coronary Artery Bypass Surgery.

Full description

The systemic inflammatory response after cardiac surgery may cause damage to the central nervous system and elevated markers of brain injury in peripheral blood. This event may be potentially related to the development of postoperative cognitive dysfunction (POCD), with incidences varying from 20 to 83%.

Enrollment: 88 estimated patients

Sex: All

Ages: 40 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients underwent for coronary artery bypass graft surgery

Exclusion criteria

• History of brain disease or dementia, other psychiatric disorders that affect cognition
• Lack of proficiency in Portuguese language