Correlation Between Melatonin Levels in Different Biological Fluids

Istituto Auxologico Italiano

Status: Enrolling

Conditions: Neurodegenerative Diseases

Treatments: Other: blood and saliva sample and lumbar puncture diagnostic for specific neurological diseases

Study type: Observational

Funder types: Other

Identifiers

NCT05784090

21C821

Details and patient eligibility

About

The goal of this observational study is to evaluate and to correlate melatonin levels in plasma, saliva and cerebrospinal fluid (CSF) samples of patients undergoing lumbar puncture diagnostic for specific neurological diseases.

Enrollment: 36 estimated patients

Sex: All

Ages: 50 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Neurodegenerative disease

Exclusion criteria

• Age < 18 years
• Pregnancy
• Coagulations disorders
• Anticoagulant therapy

Trial design

36 participants in 3 patient groups

AD

Description:

Alzheimer's Disease

Treatment:

Other: blood and saliva sample and lumbar puncture diagnostic for specific neurological diseases

NON AD

Description:

Non Alzheimer's Disease

Treatment:

Other: blood and saliva sample and lumbar puncture diagnostic for specific neurological diseases

CT

Description:

Controls

Treatment:

Other: blood and saliva sample and lumbar puncture diagnostic for specific neurological diseases