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Correlation Between Muscle Thickness and Inflammation With Ventilator Use in Critically Ill Patients

U

University of Indonesia (UI)

Status

Completed

Conditions

Ventilation Therapy; Complications

Treatments

Other: Diaphragm thickness
Other: Cross-sectional area of rectus femoris muscle
Diagnostic Test: C-Reactive Protein (CRP) Level
Other: Cross-sectional area of biceps brachii

Study type

Observational

Funder types

Other

Identifiers

NCT03933332
IndonesiaUAnes036

Details and patient eligibility

About

Decrease thickness of diaphragm muscle, cross-sectional area of rectus femoris and biceps brachii muscle, and increase in CRP would affect ventilator length of use in critically ill patients in ICU

Enrollment

52 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Patients who had Modified Rankin Score < 4 in 1 month before admitted into ICU

Exclusion criteria

  • Pregnant women
  • Patients who had intubation more than 24 hours before admitted at ICU Cipto Mangunkusumo Hospital
  • Patients who had a history or prior to thoracic or heart surgery 14 days before admission
  • Patients who had severe peripheral muscle dysfunction
  • Patients who had a history of admission in hospital for more than 2 weeks on the last 3 months
  • Patients who predicted will be using ventilator for less than 4 days
  • Patients who suffered acute respiratory distress syndrome (ARDS) with a ratio of arterial oxygen partial pressure to fractional inspired oxygen (PaO2/FiO2) less than 200
  • Patients who declined to participate in this study

Trial design

52 participants in 1 patient group

Ventilator length of use
Description:
measured in days
Treatment:
Other: Cross-sectional area of biceps brachii
Diagnostic Test: C-Reactive Protein (CRP) Level
Other: Diaphragm thickness
Other: Cross-sectional area of rectus femoris muscle

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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