Correlation Between Preoperative Images of PPGL and Intraoperative Hemodynamics

Chinese Academy of Medical Sciences & Peking Union Medical College

Status: Completed

Conditions: Paraganglioma; Pheochromocytoma

Treatments: Other: Semiquantitative 131I-MIBG Scintigraphy Assessment

Study type: Observational

Funder types: Other

Identifiers

NCT06669481

National High Level Hospital C (Other Grant/Funding Number)

K5426

Details and patient eligibility

About

This is a retrospective observational cohort study involving patients with suspected PPGLs who underwent 131I-MIBG scanning and surgical treatment between January 2020 and April 2023. The objective is to evaluate the correlation between MIBG imaging score and intraoperative hemodynamic fluctuations.

Full description

This is a retrospective observational cohort study involving patients with suspected PPGLs who underwent 131I-MIBG scanning and surgical treatment between January 2020 and April 2023. The objective is to evaluate the correlation between MIBG imaging score and intraoperative hemodynamic fluctuations.

Enrollment: 159 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with suspected PPGLs who received 131I-MIBG scintigraphy and were treated by surgery

Exclusion criteria

• 1. surgery was performed more than 6 months after 131I-MIBG scintigraphy; 2) tumor located in bladder where radioactive urine would influence assessment of tumor; 3) tumor was not resected as a whole; 4) resected tumor was not PPGLs confirmed by pathology; 5) 131I-MIBG scintigraphy images or intraoperative BP was not available for assessment.