Correlation Between Serum Anti-Müllerian Hormone & Müllerian Ducts Anomalies in Infertility

Ahmed M.Kamel

Status: Completed

Conditions: Infertility

Treatments: Other: Anti Mullerian hormone level; Mullerian duct anomaly type

Study type: Observational

Funder types: Other

Identifiers

NCT02436538

13546

Details and patient eligibility

About

Anti-Müllerian hormone (AMH), also known as Müllerian inhibiting substance, is a dimeric glycoprotein that belongs to the transforming growth factor-beta family. It is involved in the regression of the Müllerian ducts during male fetal development. In the female, AMH is solely produced by the granulosa cells of preantral and small antral follicles, and regulates ovarian activity and follicular steroidogenesis

Full description

Following approval of the internal review board of Egyptian IVF-ET center, a retrospective analysis will be undertaken where a detailed review of the patients files who underwent intracytoplasmic sperm injection (ICSI) trials starting January 2010 till January 2015 will be done.

Patients with diagnosed mullerian anomalies will have their name , age ,duration of infertility, serum FSH, LH ,& AMH levels recorded. The method of diagnosis (HSG, 3D/ultrasonography, hysteroscopy, or laparoscopy) will also be documented.

Enrollment: 226 patients

Sex: Female

Ages: 20 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• women with diagnosed mullerian anomlies whether clinically or through imaging

Exclusion criteria

• previous ovarian surgery
• ovarian drilling
• polycystic ovarian syndrome (PCOs).

Trial design

226 participants in 1 patient group

Mullerian duct anomalies

Description:

Anti Mullerian hormone level; Mullerian duct anomaly type

Treatment:

Other: Anti Mullerian hormone level; Mullerian duct anomaly type