Correlation Between Serum Progesterone Level And Primary Dysmenorrhea

Cairo University (CU)

Status: Completed

Conditions: Primary Dysmenorrhea

Study type: Observational

Funder types: Other

Identifiers

NCT06359457

P.T.REC/012/005016

Details and patient eligibility

About

This study will be conducted to determine the correlation between the levels of serum progesterone and Menstrual Symptoms In Young Females with primary dysmenorrhea.

Full description

One hundred adult females with primary dysmenorrhea will participate in this study. They will be recruited from the Gynaecological outpatient clinic, Kasr El Ainy University Hospital, Cairo, Egypt Many studies reported that primary dysmenorrhea was the result of increased prostaglandin, especially prostaglandin F2α (PGF2α) and prostaglandin E2 (PGE2) which produced the effect through the cyclooxygenase pathway, and further led to uterine ischemia hypoxia. Nevertheless the relationship between the serum progesterone level and menstrual symptoms was not completely clear. Hence, this study will investigate the association between the serum progesterone level and menstrual symptoms in young females with primaryf dysmenorrhea.

Enrollment: 100 patients

Sex: Female

Ages: 17 to 25 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. One hundreds adult females were suffered from primary dysmenorrhea.
2. Their age was ranged from 17 to 24 years.
3. Their body mass index was ranged from 20 to 25 kg/m2.

Exclusion criteria

• Any participant will be excluded from the study if they have:

  1. Irregulars or infrequent menstrual cycles.
  2. Pacemaker, Myasthenia gravis, hyperthyroidism, active tuberculosis and psychosis.
  3. Pelvic pathology.

Trial design

100 participants in 1 patient group

A group of young females with primary dysmenorrhea

Description:

One hundred young females with primary dysmenorrhea will participate in this study. They will be recruited from the Gynecological outpatient clinic, Kasr El Ainy University Hospital, Cairo, Egypt. All females should have regular menstrual cycles. Taking blood samples of 3 ml through the cubital vein to examine the levels of serum progesterone will be carried out on the 21st day of menstruation, while to assess the pain intensity of primary dysmenorrhea using the Visual Analogue Scale (VAS) and physical and psychological symptoms associated with dysmenorrhea will be assessed by menstrual symptoms questionnaire .