Correlation Between the 'Nine Holes Peg Test' Performance and the Triple Stimulation Technique Within a Group a Patients With Multiple Sclerosis

CHU Brugmann University Hospital

Status: Completed

Conditions: Multiple Sclerosis

Treatments: Other: Nine Hole Test; Device: Triple Stimulation Technique

Study type: Interventional

Funder types: Other

Identifiers

NCT02805634

CHUB-TST02

Details and patient eligibility

About

The main goal of this study is to determine if the Triple Stimulation Technique (TST) can be correlated to performance in the manual dexterity 'nine holes peg' test, within a control group and a group of patients with multiple sclerosis.

TST (Triple stimulation technique) combines two techniques used in neurologic diagnosis: magnetic stimulation and electroneuromyography. It is based on the principle of two collisions between the descending central stimulation (magnetic stimulation) and the ascending peripheric stimulation. TST allows to better quantify central nervous system diseases. The abnormal amplitude registered by TST is proportional to the intensity of conduction disorders. The evaluation of these disorders is more precise than with the magnetic stimulation technique alone.

The Nine Hole Pegs technique is a simple manual dexterity test, commonly used in ergotherapy. The participant tries to place 9 pegs in a 9 holes perforated plate, and then tries to remove them as quickly as possible. The hand must stay in a depression within the plate, thereby insuring a constant distance between the hand and the pegs.

The nine hole peg will be realized first, and the triple stimulation examination performed after. The acquired data will be analyzed in order to find a correlation between the impairment level given by these two tests.

Enrollment: 30 patients

Sex: All

Ages: 20 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

Control group:

• No history of neurological disease
• No medicines intake that could disturb performance within the tests (psychotropic medications, sedatives, anti spastic and drugs acting on neuromuscular transmission).

Multiple sclerosis group

• Multiple sclerosis diagnose. Patients followed by Dr Dachy, within the CHU Brugmann Hospital.

Exclusion criteria

• Persons carrying ferromagnetic material (implants, pacemaker).
• Epilepsy history.
• Patients who have had a head trauma with loss of consciousness and/or brain injury.
• Pregnant woman.

Trial design

Primary purpose: Diagnostic

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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30 participants in 2 patient groups

Multiple sclerosis

Experimental group

Description:

Patients with multiple sclerosis, followed by Dr Dachy within the CHU Brugmann Hospital.

Treatment:

Device: Triple Stimulation Technique

Other: Nine Hole Test

Control group

Other group

Description:

Control group without neurological pathology

Treatment:

Device: Triple Stimulation Technique

Other: Nine Hole Test