Correlation Between Various Adipokines and Vascular Inflammation Measured by Positron Emission Tomography (PET) With 18F-fluoro-deoxyglucose (FDG) (18FDG-PET)

Korea University

Status: Completed

Conditions: Atherosclerosis

Treatments: Other: Cross sectional study

Study type: Observational

Funder types: Other

Identifiers

NCT01150006

PET_Adipokines

Details and patient eligibility

About

The inflammatory state and composition of atherosclerotic plaques are considered the main contributing factors responsible for acute cardiovascular events, rather than the degree of stenosis. Recently, positron emission tomography (PET) with 18F-fluoro-deoxyglucose (FDG) has been suggested as a promising novel imaging technique to identify the inflammatory state of atherosclerotic plaque. Recently, a few clinical studies showed that circulating A-FABP level had a close relation with the development of atherosclerosis in human. Therefore, in the present study, the investigators examined the relationship between circulating A-FABP and vascular inflammation of carotid arteries measured using FDG-PET in healthy male subjects.

Enrollment: 90 patients

Sex: Male

Ages: 20 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy male volunteers for visiting routine medical check in our clinic

Exclusion criteria

• History of cardiovascular disease (myocardial infarction, unstable angina,stroke, or cardiovascular revascularization)
• Diabetes
• Hypertension
• Malignancy
• Severe renal or hepatic disease
• Subjects taking medications that might affect inflammation such as NSIAD and statin

Trial design

90 participants in 1 patient group

Healthy male participants

Treatment:

Other: Cross sectional study