Correlation Between Various Inflammatory Markers and Vascular Inflammation Measured by 18FDG-PET

Korea University

Status: Completed

Conditions: Atherosclerosis

Treatments: Other: Cross section study

Study type: Observational

Funder types: Other

Identifiers

NCT01022684

KOSEF20546

Details and patient eligibility

About

Vascular inflammation is a key factor in both the pathogenesis and outcome of atherosclerosis. Various inflammatory markers such as LpPLA2,MCP-2 and hsCRP are well-known prognostic factors for the cardiovascular event.

18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) is a promising tool for identifying and quantifying vascular inflammation within atherosclerotic plaques.Therefore, the purpose of the study is to demonstrate the correlation between various inflammatory markers and vascular inflammation detected by 18FDG-PET.

Enrollment: 150 patients

Sex: All

Ages: 20 to 88 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy patients for visiting routine medical check in our clinic

Exclusion criteria

• History of cardiovascular disease (myocardial infarction, unstable angina, stroke, or cardiovascular revascularization)
• Diabetes
• Stage 2 hypertension (resting blood pressure, ≥160/100 mmHg)
• Malignancy
• Severe renal or hepatic disease
• Subjects taking medications that might affect inflammation such as NSIAD and statin

Trial design

150 participants in 1 patient group

Healthy patients

Treatment:

Other: Cross section study