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Correlation Between Vitamin D and B Regulatory Cell in Pregnancy

A

Assiut University

Status

Unknown

Conditions

Labor, Premature

Treatments

Dietary Supplement: Investigation

Study type

Observational

Funder types

Other

Identifiers

Details and patient eligibility

About

During pregnancy , the maternal immune system is always confronted with fetal alloantigens. the immunological mechanisms that prevent the rejection of the fetus are still not under understood.

Full description

During pregnancy , the maternal immune system is always confronted with fetal alloantigens. the immunological mechanisms that prevent the rejection of the fetus are still not under understood.the fetus is normally accepted by the maternal immune system despite despite the expression of paternal alloantigens. Normally, the fetus grows and develops very well with ongoing pregnancy.

B regulatory cells are increased in pregnant women compared to non-pregnant women.

Enrollment

90 estimated patients

Sex

Female

Ages

20 to 50 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • healthy female according to the required groups

Exclusion criteria

  • patient with infectious disease , tuberculosis ,tumor ,hematologic disease,metabolic bone disease or any other connective tissue diseases were excluded.
  • Patient with viral hepatitis.
  • serological evidence of HIV infection.

Trial design

90 participants in 3 patient groups

Full term labor
Description:
Measured by flow cytometry and ELUSA
Treatment:
Dietary Supplement: Investigation
Preterm labor
Description:
Measured by flow cytometry and ELISA
Treatment:
Dietary Supplement: Investigation
Control
Description:
For comparison
Treatment:
Dietary Supplement: Investigation

Trial contacts and locations

2

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Central trial contact

Helal Hetta, Lecturer; Khalid Hassanein, Professor

Data sourced from clinicaltrials.gov

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