Correlation of Biochemical Indexes and Retinal Hemodynamic in Patients With Different Degrees of Diabetic Retinopathy

Mingzhe Cao

Status: Enrolling

Conditions: Diabetic Retinopathy

Treatments: Diagnostic Test: imaging

Study type: Observational

Funder types: Other

Identifiers

NCT05902650

MCao

Details and patient eligibility

About

All OCTA data and biochemical indexes of diabetic patients were acquired. A prediction model of diabetic retinopathy was built, and the random forest method was used to identify sensitive indicators.

Full description

Diabetic patients at the Department of Ophthalmology of the Seventh Affiliated Hospital of Sun Yat-sen University were selected as research participants. All OCTA data and biochemical indexes were acquired. A prediction model of diabetic retinopathy was built, and the random forest method was used to identify sensitive indicators.

Enrollment: 200 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Clinical diagnosis of diabetes

Exclusion criteria

• various other types of retinal and choroidal disease;
• history of any intraocular surgery or treatment (including intravitreal injection, retinal photocoagulation etc.
• with severe refractive medium opacity that could affect fundus examination.

Trial design

200 participants in 4 patient groups

Group 1

Description:

diabetic patients with no diabetic retinopathy

Treatment:

Diagnostic Test: imaging

Group 2

Description:

diabetic patients with mild nonproliferative diabetic retinopathy

Treatment:

Diagnostic Test: imaging

Group 3

Description:

diabetic patients with moderate and severe nonproliferative diabetic retinopathy

Treatment:

Diagnostic Test: imaging

Group 4

Description:

diabetic patients with proliferative diabetic retinopathy

Treatment:

Diagnostic Test: imaging