Correlation of Cerebral State Index With the Richmond Agitation-Sedation Scale in Mechanically Ventilated ICU Patients

CAMC Health System

Status: Terminated

Conditions: Sedation; Analgesia

Treatments: Device: Cerebral State Monitor

Study type: Observational

Funder types: Other

Identifiers

NCT00855075

08-03-2038

Details and patient eligibility

About

The purpose of this study is to correlate the cerebral state index obtained from a cerebral state monitor with the Richmond Agitation-Sedation Scale assessment performed on sedated and mechanically ventilated intensive care patients.

Full description

Currently there are no objective methods to measure levels of sedation in all ICU patient populations. This generally does not become problematic in most patients. However, certain populations cannot be assessed by standard means. These populations would include patients who are quadriplegic and those who are being treated with neuromuscular blocking agents. The current norm is to use a sedation scale such as the Richmond Agitation-Sedation Scale to assess the patient's level of sedation. An alternative to this would be to use an EEG based method that monitors brain activity. New methods of monitoring brain activity, using cerebral state monitors may provide an effective means of monitoring sedation. The cerebral state monitor, however, and the parameters it provides, the cerebral state index, has not been tested in an ICU setting. Correlating the measurements gained from the cerebral state monitor with the RASS assessment from sedated ICU patients may allow us to develop a method of monitoring sedation in populations that were impossible to monitor previously. Accurately monitoring the level of sedation in these patients may help decrease the incidence of over-sedation and under-sedation.

Enrollment: 3 patients

Sex: All

Ages: 18 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Admission the surgical-trauma intensive care unit at the Charleston Area Medical Center General Hospital
• Adult (18-85 years of age)
• Anticipated duration of mechanical ventilation of at least 72 hours

Exclusion criteria

• Patients admitted with paralysis or a brain injury
• Patients who are deaf, blind, or have pre-existing dementia/delirium

Trial design

3 participants in 1 patient group

Cerebral State Monitor

Description:

A cerebral state monitor will provide a cerebral state index for mechanically ventilated intensive care patients. Recorded cerebral state indexes will be correlated with clinical assessments of sedation using the Richmond Agitation-Sedation Scale.

Treatment:

Device: Cerebral State Monitor