Correlation of Insulin Resistance With Hormonal and Ovarian Morphological Characteristics in Patients With Polycystic Ovarian Syndrome

Cairo University (CU)

Status: Not yet enrolling

Conditions: Study the Relationship Between Insulin Resistance With Hormonal and Ovarian Morphological Characteristics in Patients With Polycystic Ovarian Syndrome

Treatments: Other: No intervention

Study type: Observational

Funder types: Other

Identifiers

NCT05661565

0000000 (Other Grant/Funding Number)

Details and patient eligibility

About

We designed a study to determine if ovarian volume (OV) and/or follicle number (FN) are independently associated with abnormal metabolic findings in women diagnosed with PCOS. We hypothesized that ovarian morphology but not follicle number would be associated with a significantly higher odds of hyperinsulinemia among women with PCOS.

Enrollment: 100 estimated patients

Sex: Female

Ages: 16 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

A-patients met the Rotterdam criteria of PCO with two out of three of the following:

1. oligo-or-anovulation
2. clinical and/or biochemical hyperandrogenism
3. the presence of 10 or more antral follicles in one ovary and/or a maximum ovarian volume > 10cc B-reproductive age group (16:45 years) C-BMI <40

Exclusion criteria

A-age >40 years B-BMI>40 C-previous ovarian surgery D-chronic medical disorders [DM , HTN , ...]