Cortical Cerebellar Infarctions Associated With Patent Foramen Ovale in Young Stroke Patients

Centre Hospitalier Universitaire de Nīmes

Status: Completed

Conditions: Brain Infarction

Treatments: Other: MRI scanner; Other: Contrast transoesophageal echocardiography

Study type: Observational

Funder types: Other

Identifiers

NCT04043559

Local/2019/DR-01

Details and patient eligibility

About

The investigator retrospectively analyzed consecutive young (<60 years) cryptogenic stroke patients with Patient Foramen Ovale (PFO) recruited between January 2016 and May 2019 in our center, and compared these patients with sex- and age-matched controls with cryptogenic stroke without PFO. Analyzed baseline characteristics: sex, age, cardiovascular risk factors, history of stroke, and cortical/subcortical localization, arterial territory, number of lesions, and lesion size of the acute symptomatic infarction, together with the ROPE score. The presence and the number of acute and chronic SCCI lesions were assessed.

Enrollment: 50 patients

Sex: All

Ages: 18 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• patients : young (<60 years) adult patients,
• Patient recruited and registered in our stroke database between January 2016 and May 2016 of our center (Nîmes University Hospital, France),
• Patients presenting with an acute symptomatic infarction (confirmed by diffusion-weighted MRI) of unknown origin
• Controls : age-matched controls with cryptogenic stroke without PFO

Trial design

50 participants in 2 patient groups

patients with an acute symptomatic infarction

Treatment:

Other: Contrast transoesophageal echocardiography

Other: MRI scanner

controls with cryptogenic stroke

Treatment:

Other: Contrast transoesophageal echocardiography

Other: MRI scanner