Cortical Excitability Using Transcranial Magnetic Stimulation and Neuronavigation Device (RC-TMS)

Grenoble Alpes University Hospital Center (CHU)

Status: Completed

Conditions: Healthy Volunteers

Treatments: Device: TMS "Magpro®, Magventure Inc" device

Study type: Interventional

Funder types: Other

Identifiers

NCT02596789

2012-A00316-37

Details and patient eligibility

About

This study has two main goals :

• to investigate the impact of aging on cortical excitability (CE)
• to investigate the impact of "state dependency" on CE, using a cognitive task and an emotional one.

A Neuronavigation system of transcranial magnetic stimulation is used, and electromyographic response are recorded.

Enrollment: 75 patients

Sex: All

Ages: 18 to 75 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• male or female
• age 18-75
• signed informed consent
• normal physical examination

Exclusion criteria

• less 18 or more 75 years of age
• contra indication to TMS: epilepsia or seizures, metallic head devices, cardiac pacemaker, pregnancy, jet lag or severe insomnia the night before
• severe physical disease
• treatment with psychotropic drugs
• overt psychiatric disease
• alcohol consumption before the examination

Trial design

Primary purpose: Basic Science

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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75 participants in 1 patient group

state dependency TMS

Other group

Description:

TMS performed at rest and during a cognitive/emotional task

Treatment:

Device: TMS "Magpro®, Magventure Inc" device