Cortical Processes During Walking Post-stroke

University of Florida

Status: Completed

Conditions: Walking, Difficulty; Stroke, Acute

Study type: Observational

Funder types: Other

Identifiers

NCT05710029

IRB202202100

Details and patient eligibility

About

The study aims to use novel mobile imaging techniques with high-density electroencephalography (EEG) to quantify cortical processes synchronized to the biomechanics of walking. Here, the study has two aims - the primary aim is to quantify the cortical processes that contribute to gait dysfunction early post-stroke, and the second aim is to determine how cortical processes are mediated by mechanical assistance during early gait training post-stroke.

Participants will wear an electroencephalography (EEG) cap to measure brain activity and other non-invasive physiological sensors. Participants will be asked to perform different tasks, such as walking at different speeds and walking with different levels of body weight support.

Full description

This study will recruit 15 subacute post-stroke individuals and 15 age-matched neurotypical individuals between the age of 18-80 years old.

Enrollment: 30 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria for post-stroke patients:

• Participants will have a unilateral brain lesion within six months prior to participation in this project;
• Paresis confined to one side;
• Ability to walk for 10 meters continuously;
• Absence of severe cognitive dysfunction as demonstrated by a Mini-Mental score greater than 24;
• Absence of severe concurrent medical problems;
• Ability to provide informed consent.

Exclusion Criteria for age-matched adults:

• Any major neurological, cardiovascular, orthopedic, and psychiatric diagnoses