Corticosteroid Intralesional Injection as an Alternative Treatment in Oral Pyogenic Granuloma in the Esthetic Zone.

Beni-Suef University

Status and phase: Enrolling; Phase 3; Phase 2

Conditions: Oral Pyogenic Granuloma

Treatments: Drug: Solu-Cortef

Study type: Interventional

Funder types: Other

Identifiers

NCT05534334

17/4/21

Details and patient eligibility

About

Gingival Pyogenic granuloma in the esthetic zone represents an esthetic problem. While surgical treatment may not give the premium esthetic demands, corticosteroid may acheive this balance.

Full description

In our practice, the investigators have found the use of topical steroids effectively induced regression of PGs. This protocol has been suggested by published case reports supported by the anti-inflammatory actions corticosteroid.

This is a particularly valuable approach for patients who have PG in the esthetic zone allowing the surgeon to keep maximum amount of periodontal tissues.

Enrollment: 30 estimated patients

Sex: All

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients with oral pyogenic granuloma at the esthetic zone

Exclusion criteria

• Patients who were not compliant to oral hygiene instructions and can not be motivated

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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30 participants in 2 patient groups

Control arm

Active Comparator group

Description:

Surgical excision of the gingival pyogenic granuloma

Treatment:

Drug: Solu-Cortef

Intervention

Experimental group

Description:

Intralesional injection with corticosteroids solution (1.8 mL of 100 mg hydrocortisone)

Treatment:

Drug: Solu-Cortef