Corticosteroids for the Prevention of Atrial Fibrillation After Cardiac Surgery

Kuopio University Hospital

Status: Terminated

Conditions: Atrial Fibrillation

Treatments: Drug: intravenous hydrocortisone

Study type: Interventional

Funder types: Other

Identifiers

NCT00442494

KUH5204515

Details and patient eligibility

About

Atrial fibrillation is the most common arrhythmia to occur after cardiac surgery. Inflammatory response may be one etiological factor.

We hypothesized that intravenous corticosteroid administration after cardiac surgery prevents AF after cardiac surgery.

Enrollment: 1 patient

Sex: All

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients scheduled to undergo their first on-pump CABG, aortic valve replacement or combined aortic valve replacement and CABG were enrolled.

Exclusion criteria

• Previous episodes of AF or flutter
• Uncontrolled diabetes mellitus
• Systemic mycotic infection
• Active tuberculosis
• Cushing's syndrome
• Psychotic mental disorder
• Herpes Simplex keratitis
• Serum creatinine exceeding 200 µg/ml
• Patients were also excluded if they had a history of previous peptic ulcer or thrombophlebitis.

Trial design

1 participants in 1 patient group

Study couldn´t start due to investigator

Other group

Description:

Study couldn´t start due to investigator

Treatment:

Drug: intravenous hydrocortisone