Costotransverse Foramen Block Versus Thoracic Paravertebral Block in Thoracotomy for Lung Cancer

National Cancer Institute, Egypt

Status: Enrolling

Conditions: Thoracotomy; Thoracic Paravertebral Block; Lung Cancer; Costotransverse Foramen Block

Treatments: Other: Thoracic paravertebral plane block; Other: Costotransverse foramen block

Study type: Interventional

Funder types: Other

Identifiers

NCT07367581

AP2512-501-141-205

Details and patient eligibility

About

This study aims to compare the costotransverse foramen block (CTFB) with thoracic paravertebral block (TPVB) in patients undergoing thoracotomy for lung cancer.

Full description

Thoracotomy is known to be one of the most painful surgeries. Managing post-thoracotomy pain is a major clinical challenge, as about 75% of patients report moderate to severe pain afterward.

Various regional and central analgesia techniques, such as thoracic epidural analgesia (TEA), thoracic paravertebral block (TPVB), and erector spinae plane block (ESPB), are employed in a multimodal approach. Although TEA has traditionally been considered the gold standard for thoracotomy pain control, concerns about its side effects have prompted the exploration of alternatives.

The costotransverse foramen block (CTFB), a recently introduced technique, has been examined in both cadaveric and case studies.

Enrollment: 70 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age > 18 years and ≤ 65 years old.
• American Society of Anesthesiologists (ASA) physical status II-III.
• Body mass index 18-35 kg/m2.
• Patients scheduled for thoracotomies for lung cancer.

Exclusion criteria

• Patient refusal.
• History of sensitivity to local anesthetics.
• History of psychological disorders.
• Contraindication to regional anesthesia, e.g., local sepsis, pre-existing peripheral neuropathies, and coagulopathy.
• Severe respiratory, cardiac, hepatic, or renal disease.
• Morbid obesity.
• Uncooperative patients.
• Patients on chronic pain therapy.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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70 participants in 2 patient groups

CTFB Group

Experimental group

Description:

Patients will receive an ipsilateral ultrasound-guided costotransverse foramen block with injection of 20 ml bupivacaine 0.25%.

Treatment:

Other: Costotransverse foramen block

TPVB Group

Experimental group

Description:

Patients will receive an ipsilateral ultrasound-guided thoracic paravertebral plane block with injection of 20 ml bupivacaine 0.25%.

Treatment:

Other: Thoracic paravertebral plane block