Cough Peak Flow for Extubation Prediction (CPF)
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About
Successful weaning from mechanical ventilation in ICU patients depends on patient ability to breathe spontaneously and on cough efficiency. Previous studies found that cough peak flow (CPF) at 60 L/min threshold predicted extubation failure. These studies measured CPF using a dedicated flow-meter that required patient disconnection from the ventilator, limiting the generalizability of this procedure. This study aimed to predict extubation outcome in a consecutive series of patients by measuring CPF from the ventilator flow-meter. CPF measurements were done by freezing ventilator screen and scrolling the cursor to the maximal value of CPF during expiration and Tidal Volume (TV) in preceding inspiration.
The objective was to assess the performance of CPF to predict early extubation outcome.
Enrollment
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Volunteers
Inclusion criteria
- Age > 18 years
- Intubation > 24h
- Eligible for scheduled weaning trial and then scheduled extubation
- Mechanical ventilation from Evita XL ventilator (Dräger, Germany)
- Patient's agreement to participate
Exclusion criteria
- Withdrawal decision of life supporting care
Trial contacts and locations
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Data sourced from clinicaltrials.gov
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