COVID-19 and Chilblains (ECCES)

Rennes University Hospital

Status: Completed

Conditions: COVID-19; Chilblains

Treatments: Other: Biological sample collection

Study type: Interventional

Funder types: Other

Identifiers

NCT04455308

35RC20_8888_ECCES

Details and patient eligibility

About

Chilblains (inflammatory lesion of the feet or hands) have been reported with an unusual frequency during the confinement period, most commonly in children, teenagers and young adults. The aim of the ECCES study is to find out whether these manifestations of chilblains can be linked to the SARS-CoV-2 coronavirus.

For this, an epidemiologic study will compare two types of family (or more precisely people who were confined together in March-April-May):

• "case family" in which at least one of the members had chilblains
• "comparator family" in which none of the members had chilblains Environment (home lockdown) of the two types of family will be analyzed. Each member of the "family" will be suggested doing a serological test.

Enrollment: 269 patients

Sex: All

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• "case family"
• at least one of the members with chilblains
• diagnosis of chilblains (anamnesis and pictures) written informed consent
• "comparator family"
• none of the members with chilblains
• one member matched on age (+/- 1 year) to a patient with chilblains
• written informed consent

Exclusion criteria

• Subject legally protected (under judicial protection, guardianship), persons deprived of liberty

Trial design

Primary purpose: Other

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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269 participants in 2 patient groups

Subjects with chilblains

Experimental group

Treatment:

Other: Biological sample collection

Subjects without chilblains

Active Comparator group

Treatment:

Other: Biological sample collection