COVID-19: Early Detection of Worsening by Voice and Respiratory Pattern Characteristics (COVOICE)

Direction Centrale du Service de Santé des Armées

Status: Enrolling

Conditions: COVID-19; Sars-CoV-2 Infection

Treatments: Device: COVOICE application use - follow-up; Device: COVOICE application use - initial

Study type: Observational

Funder types: Other

Identifiers

NCT05892549

2020-COVID19-21

2020-A03182-37 (Other Identifier)

Details and patient eligibility

About

In some clinical forms of COVID-19, an uncontrolled hyper-inflammatory reaction known as a "cytokine storm" appears abruptly, around day 7, and is associated with rapid respiratory deterioration, requiring hospitalization in an intensive care unit (ICU).

At present, although risk factors for this severe form have been described, there are no validated criteria for determining which individual patients will develop this aggravation.

The study of respiratory sounds (amplitude, frequency, ...) has made it possible in other respiratory pathologies (e.g., chronic obstructive pulmonary disease) to predict exacerbations several days in advance.

Having a predictive respiratory pattern for worsening in COVID-19 would make it possible to anticipate the need for intensive care hospital beds, by means of a tool easily available on a mobile phone.

Enrollment: 1,188 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• French speaking
• Affiliated to a social security system
• Owning a mobile phone capable of accessing the COVOICE application

Exclusion criteria

• Incapable adults
• People deprived of their liberty
• People under administrative or judicial supervision
• Patients intubated or hospitalized in intensive care unit

Trial design

1,188 participants in 3 patient groups

COVID

Treatment:

Device: COVOICE application use - follow-up

Other respiratory diseases

Treatment:

Device: COVOICE application use - follow-up

Healthy

Treatment:

Device: COVOICE application use - initial