COVID-19 Immune Repertoire Sequencing (IMSEQ)

Institute of Tropical Medicine, Belgium

Status: Completed

Conditions: SARS-CoV 2; Corona Virus Infection; B Cell; COVID; RDT

Study type: Observational

Funder types: Other

Identifiers

NCT04368143

IMSEQ

Details and patient eligibility

About

This concerns a single-center prospective interventional cohort study. Laboratory-confirmed COVID-19 patients will be asked to donate blood at at least two different timepoints. This will allow us to investigate T and B cell evolutions during the course of infection and recovery. The expected duration of the study is four months or the total duration of the SARS-CoV-2 circulation in Belgium (whichever is shortest).

Enrollment: 84 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• laboratory confirmed COVID-19 acute infection
• be older than 18 years of age
• be hospitalized at the UZA
• willing and able to provide written informed consent by the participant or its legal representative (for instance in case of medical incapacitation)

Exclusion criteria

• younger than 18 years old
• Ambulatory patients