COVID-19 in Baselland: Validation of Simple and Accurate Tests for COVID-19 Detection, Monitoring and Tracing (ACCURATE-BL-COVID-19)

University Hospital Basel

Status

Enrolling

Conditions

Coronavirus Infectious Disease 2019 (COVID-19)

Treatments

Other: Validation of the NGS method

Other: Saliva based assay: crude RNA extraction

Other: Validation of the POCT Antigen and Antibody tests

Other: Validation of the LAMP assays

Study type

Observational

Funder types

Other

Identifiers

NCT04625257

2020-01112 ch20Savic2;

Details and patient eligibility

About

This study is to establish an accurate, robust and easily scalable COVID-19 viral nucleic acid analysis platform from, but not limited to, saliva to help enable and support contact tracing in the canton of Baselland/ Switzerland. To achieve this, crude ribonucleotide acid (RNA) extraction from saliva is validated in combination with next-generation sequencing (NGS) diagnostics and loop mediated amplification (LAMP) assays as well as point of care test (POCT) for rapid detection of viral antigens on patients' samples.

Enrollment

1,600 estimated patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria