COVID-19 Infection and Idiopathic Membranous Nephropathy

Capital Medical University

Status: Enrolling

Conditions: Idiopathic Membranous Nephropathy

Study type: Observational

Funder types: Other

Identifiers

NCT05691179

2022-P2-429-01

Details and patient eligibility

About

Infection is one of common risk factors for relapsing of idiopathic membranous nephropathy (IMN). However, it is still unclear wheather COVID-19 infection can induce the relapsing of IMN. Herein, in this prospective, multi-center, cohort study, the investigator enrolled the IMN patients with COVID-19 infection.

All subjects will be followed for three months with four visits at 1, 2 and 3 months. Then the investigator will compare the rate of replase of IMN in the two groups to evaluate the association of COVID-19 infection and replapse of IMN.

Enrollment: 130 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. the status of nephrotic syndrome is complete remmision or partial remmision;
2. estimated glomerular filtration rate (eGFR according to the CKD-EPI formula) ≥60 mL/min per 1.73 m2;
3. patients with a moderate risk of IMN.

Exclusion criteria

1. secondary causes of MN;
2. the labarotary data two months before enrolement is absent.

Trial design

130 participants in 1 patient group

COVID-19 infection group

Description:

the patients with IMN and COVID-19 infection