COVID-19 Stroke Apical Lung Examination Study

King's College Hospital NHS Trust

Status: Unknown

Conditions: Stroke Hemorrhagic; Covid19; Stroke, Acute; Stroke, Ischemic

Study type: Observational

Funder types: Other

Identifiers

NCT04640428

COVID SALES 2

Details and patient eligibility

About

Multi-centre prospective study evaluating computed tomography angiography studies performed for stroke patients as a diagnostic and prognostic imaging biomarker.

Full description

Diagnosis of coronavirus disease 2019 (COVID-19) relies on clinical features and reverse-transcriptase polymerase chain reaction (RT-PCR) testing. The latter is constrained by limited sensitivity and a timescale of hours to yield results, with no point-of-care test widely available. A dedicated computed tomography study of the chest is likely to be more sensitive than RT-PCR for COVID-19. Carotid computed tomography angiography (CTA) is a routine acute stroke investigation and includes the lung apices. We aim to assess the lung apices on CTA for ground glass opacification and compare this with COVID-19 RT-PCR test results and clinical outcome measures.

Enrollment: 2,000 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

All adult patients presenting with clinical features of acute ischaemic stroke undergoing investigation with computed tomography angiography at presentation.

Exclusion criteria

Poor image quality. No radiologist report available. Computed tomography angiography performed in a non-acute setting.