CPAP Versus Bilevel Pressure Support Ventilation in Cardiogenic Pulmonary Edema

University Hospital, Rouen

Status and phase: Completed; Phase 3

Conditions: Severe Acute Cardiogenic Pulmonary Edema

Treatments: Device: Boussignac CPAP - bilevel ventilation support

Study type: Interventional

Funder types: Other

Identifiers

NCT00213681

2001/059/HP

Details and patient eligibility

About

To evaluate whether bilevel positive airway pressure more rapidly improves ventilation than continuous positive airway pressure (CPAP) in patients with acute pulmonary edema. CPAP is delivered via a simple device connected to oxygen.

Sex: All

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• age > 16 yrs, acute onset of severe respiratory distress, bilateral rales and typical findings of congestion on chest radiograph
• breathing frequency of > 30/min, SpO2 >90%, use of accessory respiratory muscles

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)