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Craniopharyngioma With Tumoral Hemorrhage

T

Tongji Hospital

Status

Completed

Conditions

Apoplexy
Craniopharyngioma

Treatments

Other: intratumoral hemorrhage

Study type

Observational

Funder types

Other

Identifiers

NCT04937335
kaishu1

Details and patient eligibility

About

Clinical data of 185 consecutive patients receiving resective operation with a pathological diagnosis of craniopharyngioma in our hospital between January 2013 and February 2021 were collected. Among these patients, 18 of them were recognized as craniopharyngioma with tumoral hemorrhage during the operation.

Full description

For each case, age, gender, smoking status, alcohol intake, past history, symptoms, blood pressure, blood cell count, blood biochemical tests, coagulation tests, hormone tests, radiological results, surgical treatment and the outcome at discharge were collected. The first test result after admission and before the operation was taken for the items of blood tests with multiple times in the analysis.

Enrollment

185 patients

Sex

All

Volunteers

No Healthy Volunteers

Inclusion criteria

  • receive resective operation with a pathological diagnosis of craniopharyngioma in our hospital
  • enter our hospital between January 2013 and February 2021

Exclusion criteria

  • have a non-craniopharyngioma or unverified pathological diagnosis at discharge
  • have received surgical or radiological treatment on the sellar region
  • receive treatment of coagulation modulation, immunosuppressive agents or chemotherapeutic drugs
  • combine with other clinical emergencies including acute myocardial infarction, cerebral stroke, trauma and sepsis at admission
  • have been diagnosed with other tumors, hematological diseases, autoimmune diseases, liver failure or renal failure

Trial design

185 participants in 2 patient groups

Non-hemorrhage group
Description:
Patients recognized as craniopharyngioma pathologically without tumoral hemorrhage observed during the operation
Hemorrhage group
Description:
Patients recognized as craniopharyngioma pathologically with tumoral hemorrhage observed during the operation
Treatment:
Other: intratumoral hemorrhage

Trial contacts and locations

0

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Data sourced from clinicaltrials.gov

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