Creatine Supplementation and Bone Mass

University of Sao Paulo

Status: Completed

Conditions: Osteoporosis; Osteopenia

Treatments: Dietary Supplement: creatine supplementation; Other: exercise training; Other: placebo (dextrose)

Study type: Interventional

Funder types: Other

Identifiers

NCT01163370

creatine and bone

Details and patient eligibility

About

Resistance training as well as creatine supplementation may increase bone mass. Therefore, the investigators speculate that resistance training combined with creatine supplementation would promote additive benefits on bone mass in elderly women with osteopenia and osteoporosis.

Enrollment: 60 patients

Sex: Female

Ages: 60+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• osteopenia and osteoporosis
• women older than 60 years old

Exclusion criteria

• cardiovascular diseases or muscular disturbances precluding exercise training
• drugs affecting bone metabolism

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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60 participants in 4 patient groups, including a placebo group

control and exercise

Placebo Comparator group

Description:

this is trained and receives placebo

Treatment:

Other: placebo (dextrose)

Other: exercise training

creatine

Experimental group

Description:

this is non-exercise trained and receives creatine supplementation

Treatment:

Dietary Supplement: creatine supplementation

exercise and creatine

Experimental group

Description:

this is exercised trained and receives creatine supplementation

Treatment:

Other: exercise training

Dietary Supplement: creatine supplementation

placebo

Placebo Comparator group

Description:

this only receives placebo (dextrose)

Treatment:

Other: placebo (dextrose)