Creatine Supplementation and Cognitive and Physical Tests (CREA)

Vrije Universiteit Brussel

Status: Completed

Conditions: Healthy; Creatine Supplementation

Treatments: Dietary Supplement: Calcium lactate; Dietary Supplement: Creatine

Study type: Interventional

Funder types: Other

Identifiers

NCT03352128

CREA

Details and patient eligibility

About

To assess whether brain creatine availability has an effect on cognition. To do so we will seek to increase brain creatine concentration via a creatine supplementation protocol.

Enrollment: 14 patients

Sex: All

Ages: 18 to 35 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy (No neurological illness including cardiovascular, renal, and endocrine disorder)
• Male/female
• No medication / supplements
• Non-smoker
• Low to moderately active
• Between 18 and 35 years old

Exclusion criteria

• Injuries
• Illness
• Use of medication
• Use of creatine in the last 3 months
• History of head trauma or seizure
• Vegetarian diet [24]
• Not being able to follow up the restrictions and prohibitions for the subjects (see Restrictions and prohibitions for the subjects)

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Triple Blind

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14 participants in 2 patient groups, including a placebo group

Creatine supplementation

Experimental group

Description:

7-day creatine supplementation

Treatment:

Dietary Supplement: Creatine

Placebo supplementation

Placebo Comparator group

Description:

7-day calcium lactate supplementation

Treatment:

Dietary Supplement: Calcium lactate