Creatine Supplementation At Simulated Altitude

California Polytechnic State University (Cal Poly)

Status: Enrolling

Conditions: Exercise Performance

Treatments: Dietary Supplement: Placebo; Dietary Supplement: Creatine

Study type: Interventional

Funder types: Other

Identifiers

NCT06489587

2023-233

Details and patient eligibility

About

Creatine supplementation has been shown to increase exercise performance at sea level. The goal of this study is to determine the effects of creatine supplementation on exercise performance at simulated altitude.

Full description

Military personnel often encounter harsh environments such as high altitudes and hypoxic conditions, leading to significant constraints on their exercise capacity and performance. At sea-level creatine supplementation increases exercise performance; however no experimental studies have examined the effect of creatine supplementation at simulated altitude. The overall objective of this study is to investigate the effects of creatine supplementation on exercise performance, via a repeated sprints test (Wingate Test) after a 2-day supplementation period, compared to a placebo group.

Enrollment: 60 estimated patients

Sex: All

Ages: 18 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• 18-40 years old
• BMI 18.5 to 40 kg/m2
• Habitually active (>150 minutes per week of moderate-vigorous physical activity)

Exclusion criteria

• Pregnant or trying to become pregnant
• Recent use of creatine supplementation
• Supplemental allergies

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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60 participants in 2 patient groups

Placebo Supplementation

Active Comparator group

Description:

Participants given Placebo (20 grams of glucose) daily in 5-gram servings (4 capsules), 4 times per day for 2 days.

Treatment:

Dietary Supplement: Placebo

Creatine Supplementation

Experimental group

Description:

Participants given Creatine (20 grams of glucose) daily in 5-gram servings (4 capsules), 4 times per day for 2 days.

Treatment:

Dietary Supplement: Creatine