Creatine Supplementation in Autism Spectrum Disorder (CREATOR)

University of Novi Sad, Faculty of Sport and Physical Education

Status: Active, not recruiting

Conditions: Autism Spectrum Disorder

Treatments: Dietary Supplement: Creatine

Study type: Interventional

Funder types: Other

Identifiers

NCT04498078

ABL-21-AUCR

Details and patient eligibility

About

Autism Spectrum Disorder (ASD) is accompanied by reduced levels of total creatine in right temporal-parietal junction and other brain regions of interest, and addressing this deficit by exogenous administration of creatine may have beneficial effects on brain metabolism and disease-specific clinical symptoms in patients suffering from ASD.

Enrollment: 20 patients

Sex: All

Ages: 10+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age 10 years and above
• Informed consent signed by a parent or legal guardian or legal representative
• Diagnostic and Statistical Manual of Mental Disorders-IV criteria for ASD.

Exclusion criteria

• Pregnant or nursing female patients
• Non-pharmacologic therapy
• Current diagnosis of other mental disorder

Trial design

Primary purpose: Supportive Care

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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20 participants in 1 patient group

Creatine

Experimental group

Description:

Twenty grams per day b.i.d.

Treatment:

Dietary Supplement: Creatine