Creation of a Biospecimen Repository From Patients With Interstitial Lung Diseases (ILD)

Mayo Clinic

Status: Enrolling

Conditions: Interstitial Lung Disease

Treatments: Other: Pneumonia; Other: Healthy; Other: ILD

Study type: Observational

Funder types: Other

Identifiers

NCT03478826

17-008088

Details and patient eligibility

About

To develop a repository of blood samples from patients with ILD to support future studies into the development of such biomarkers. Patients with pneumonia and healthy patients will also be recruited as a control group.

Full description

The proposed biospecimen repository would be derived from patients diagnosed with ILD. This is to include 500 patients in the repository, with each patient contributing one blood sample. Patients with pneumonia and healthy patients will also be recruited as a control group.

Enrollment: 635 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients with a diagnosis of ILD or any fibrotic disease of the lung or a diagnosis of pneumonia
• Patients willing to provide written informed consent

Exclusion criteria

• Unwillingness/unable to give blood samples

Trial design

635 participants in 3 patient groups

ILD

Description:

250 patients (male and females \>18 years of age) with the diagnosis of fibrotic DILD (IPF (n=100), fibrotic NSIP (n=50), chronic hypersensitivity pneumonia (n=20), sarcoidosis(n=50), progressive rheumatoid lung disease (n=10) and scleroderma lung disease (n=20), 10 patients with other fibrosing disease (fibrosing mediastinitis), and 50 patients with lymphangioleiomyomatosis.

Treatment:

Other: ILD

Healthy

Description:

100 healthy participants as a control group.

Treatment:

Other: Healthy

Pneumonia

Description:

25 patients with pneumonia as a control group.

Treatment:

Other: Pneumonia