Creation of a Probabilistic Atlas of Normal Cerebral Uptake of 18F-FDG in PET/MRI. (ATLATEP)

Institut de cancérologie Strasbourg Europe

Status

Completed

Conditions

Brain Diseases

Treatments

Diagnostic Test: brain PET-MRI with 18F-FDG

Study type

Interventional

Funder types

Other

Identifiers

NCT05355857

2021-008

Details and patient eligibility

About

With 18F-FDG PET, we have few atlases of normality allowing the realization of objective quantitative analyses. An atlas of normality is a probabilistic atlas of normal FDG uptake from a representative set of brain PET images of healthy subjects. This type of atlas is essential for intra- and inter-individual comparisons.

Accurate quantitative analysis of brain 18F-FDG PET images acquired on a hybrid PET system has been shown to require an institutional normal database for statistical analyzes (Akdemir et al., JNM 2017 and Della Rosa et al Neuroinformatics, 2014).

Full description

This is a prospective, monocentric, non-randomized study, with no direct individual benefit since it involved healthy volunteers.

Enrollment

39 patients

Sex

All

Ages

18+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Male or female aged 20 to 50
Absence of any history or cardiovascular, neurological or psychiatric deficit
Signed the informed consent

Exclusion criteria

Contraindication to the realization of an MRI or PET and to the injection of 18F-FDG
People using a pacemaker or insulin pump
People wearing a metal prosthesis or an intracerebral clip
People with intraocular metal splinters
People with a pathology considered incompatible for the production of the atlas according to the investigator
Pregnant women and breastfeeding women
Subject in period of exclusion.